Leslie B. Gordon,Mark W. Kieran,Monica E. Kleinman
申请号:
US15201525
公开号:
US10098871B2
申请日:
2016.07.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are combination therapies for the treatment of progeroid diseases and conditions, cellular aging, bone diseases, and cardiovascular diseases. The provided combination therapies target the aberrant farnesylation of the mutant lamin A protein progerin and increase progerin clearance.