YONSEI UNIVERSITY;HUONS CO., LTD.;INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY;INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
HWANG, SUNG JOO,CHA, KWANG HO,KANG, HAN,SUN, BO KYUNG
申请号:
SG11201407089S
公开号:
SG11201407089SA
申请日:
2013.01.22
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
Provided is an ophthalmic composition containing cyclosporine as an active ingredient and including polyethoxylated castor oil or polyethoxylated hydrogenated castor oil, and a method of preparing the same. Particularly, the ophthalmic composition is prepared as a nanoemulsion having a particle diameter of 100 nm or less simply by mixing and stirring an oil phase and an aqueous phase without using a high speed stirring or shearing machine, so that it is very physiochemically stable and storable for a long time. In addition, the ophthalmic composition causes no irritation to eyes.