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CONJUGUÉS ET INHIBITEURS DE PROTÉINE KINASE
专利权人:
CELGENE AVILOMICS RESEARCH; INC.
发明人:
SINGH, JUSWINDER,PETTER, RUSSELL COLYN,NIU, DEQIANG,QIAO, LIXIN,KLUGE, ARTHUR,LOBB, ROY,GHOSH, SHOMIR,ZHU, ZHENDONG
申请号:
EP10817748
公开号:
EP2478361A4
申请日:
2010.09.15
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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