Inhibiteurs de Janus kinases

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

申请号：

EP09800714.9

公开号：

EP2278969B1

申请日:

2009.04.09

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3, TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

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