The present Invention relates to substituted Spiro - amide compounds of the General formula I, represented by a D1 or D2 radical B is C (= o), S (= o) 2 or group - C (= o) - N (R9), in which the nitrogen atom of the latter is linked to the radical R1 and Q1, Q2, independently Nte one another represent C, N or CH C1 r1 represents alkyl -, aryl, heteroaryl, CH (aryl) 2C3 - 8 - cycloalkyl or an aryl, heteroaryl or C3 - 8 - linked through a cycloalkyl Group 6 - alquileno C1 - C2 - 6 -, a group or a group alquenileno C2 - 6 - alquinileno, or an aryl or heteroaryl Group linked by a group C3 - 6 cicloalquileno R2 represents h, C1 - 6 C3 alkyl, cycloalkyl - 8 -, aryl, het Eroarilo C3 - 8 - or cycloalkyl,Aryl or heteroaryl Group linked by a C1 - 6 - alquileno R3 and R4 with the Group - Q1 - Q2 - this together to form a ring, which is insustituido or substituted in one or more of its members to the carbon Ring by one or more substituents, independent of each other, elected Group consisting of F, CI, BR, I, CF3, C1 - 6 - 6 or - C1 - alkyl, alkyl, Oh, ocf3, sh, scf3,Aryl and heteroaryl and \/ or may merge with at least an aryl or heteroaryl, where the ring is saturated or unsaturated, aromatic once or several times, is 4 -, 5 -, 6 - or 7 - member, and may optionally contain one or more heteroatoms heteroatoms or group independent of one another. Choose Os group consisting of N, nr50, o, S, S (= o) and S (= o) 2 where the radical R50 denoted C1 - 6 h, alkyl,- C (= o) - 8 - C3 - R51, cycloalkyl, aryl, heteroaryl or C3 - 8 - cycloalkyl, aryl or heteroaryl Group linked by a alquileno C1 - 3 -, 6 - and R51 denoted C1 - C3 - 8 - alkyl, aryl, heteroaryl cicloalquiio, a cycloalkyl or C3 - 8 - aryl or heteroaryl, linked by a group C1 - 3 - alquileno R5 representation NTA 0, 1, 2, 3 or 4 substituents, independently of each other,Are selected from the group consisting of F, CI, CF3, ocf3, Oh, C1 - 6 - 6 or - C1 - alkyl and alkyl substituents and \/ or two adjacent R5 is an aryl or heteroa
