Compound FEN\u00d3LICO and combination of 1,4 dihydropyridine fused with a benzodiazepine for the treatment of disorders of the central nervous system and vascular
- 专利权人:
- CENTRO DE INVESTIGACIÓN Y DESARROLLO DE MEDICAMENTOS (CIDEM). ORGANIZACION SUPERIOR DE DIRECCION EMPRESARIAL BIOCUBAFARMA
- 发明人:
- Bárzaga Fernández, Pedro Gilberto,Canaán-Haden Navarro, Claudia Amanda,Delgado Hernández, René,Fonseca Fonseca, Luis Arturo,González Alfonso, Nicté,Mondelo Rodríguez, Abel,Nuñez Figueredo, Yanier,Ocho
- 申请号：
- CU20160142
- 公开号：
- CU20160142A7
- 申请日:
- 2016.09.27
- 申请国别(地区):
- CU
- 年份:
- 2018
- 代理人:
- 摘要：
- < p > The present Invention relates to the ChemicalThe pharmaceutical and in particular with the obtaining of formulations derived from phenolic or polyphenolic compounds and Derivatives of phenolic or polyphenolic compounds combinesTwo Systems of benzodiazepine FUSED tricyclic Derivatives of 1,4 - dihydropyridines with Action on the central nervous and vascular Systems.These Pharmaceutical compositions are gaba\u00e9rgica Action, antiglutamat\u00e9rgica, Modulating calcium channels, mitoprotectora, Antioxidant, anti-inflammatory and antiapoptotic,Used in the treatment of cardiovascular, cerebrovascular, neurodegenerative and Neuropsychiatric and neurological. < \/ p >
La presente invención se relaciona con Ia Química, Ia Farmacéutica y en particular con Ia obtención de formulaciones a partir de derivados de compuestos fenólicos o polifenólicos y a partir de derivados de compuestos fenólicos o polifenólicos combinados con sistemas tricíclicos del tipo benzodiazepinas fusionadas a derivados de 1,4-dihidropiridinas con acción sobre el Sistema Nervioso Central y Vascular. Estas composiciones farmacéuticas presentan acción GABAérgica, antiglutamatérgica, moduladora de los canales de calcio, mitoprotectora, antioxidante, antiinflamatoria, y antiapoptótica, utilizables en el tratamiento de las enfermedades cardiovasculares, cerebrovasculares, neurodegenerativas, neuropsiquiátricas y neurológicas.
- 来源网站：
- 中国工程科技知识中心
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相关专利
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- TRICYCLIC AND TETRACYCLIC SYSTEMS WITH ACTIVITY ON THE CENTRAL-NERVOUS AND VASCULAR SYSTEMS
- Phenolic compound and its combination with benzodiazepine condensed with 1,4-dihydropyridine for the treatment of diseases of the central nervous and vascular systems
- INDOLAMINE DERIVATIVES FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM
