MEIER, CHRISTIAN,NOLLENBERGER, KATHRIN,GRYCZKE, ANDREAS,PETEREIT, HANS-ULRICH,DRESSMAN, JENNIFER
申请号：
CA2641351
公开号：
CA2641351C
申请日:
2007.01.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to a pharmaceutical composition, containing a mixture ofat least one cationic water-soluble (meth)acrylate copolymer, at least onewater-insoluble polymer and at least one active agent with a solubility indemineralised water of 3,3 g/l or less, characterised in that the water-insoluble polymer and the active agent are present in a ratio of at most 3.5to 1 parts by weight and the pharmaceutical composition has the followingproperties: the contained active agent is released in dissolved form in amedium buffered at pH 1.2, which, after 2 hours at pH 1.2, corresponds to atleast 16 times the solubility value of the active agent alone at pH 1.2.
