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激酶抑制劑化合物的多晶型、含其的藥物組合物及其製備方法和應用
专利权人:
BETTA PHARMACEUTICALS CO., LTD;貝達藥業股份有限公司
发明人:
LIANG, Congxin,XIE, Lihua,XIE, Lihua,謝利華
申请号:
HK18116171
公开号:
HK1257194A1
申请日:
2018.12.18
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
The invention discloses polymorphic forms of a compound of formula I, pharmaceutical compositions containing same, preparation method therefor and use thereof. The compound of formula I of the present invention is as shown in formula I, of which the crystalline form can be crystalline form 1, crystalline form 2, crystalline form 3, crystalline form 5, crystalline form 6 or crystalline form 7. All the crystalline forms of the compound of formula I in the present invention have good crystalline stability and chemical stability and a decrease in purity of their main ingredient less than 2%. The preparation method of the present invention may be used to produce the various crystalline forms of the compound of formula I with high purity, and suitable for large scale production.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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