The invention provides a method for obtaining a composition, the method comprising the steps of: (a) combining an amount of an active agent with a carrier to provide a diluted formulation； (b) taking an amount of diluted formulation and combining it with carrier to provide a more diluted formulation； (c) taking an amount of the more diluted formulation and combining it with carrier to provide a yet more diluted formulation, (d) repeatedly carrying out the step of taking the most diluted version of the formulation and combining an amount of said formulation with carrier, until a final formulation is obtained where the concentration of the active agent is less than 1 x 10
