PROBLEM TO BE SOLVED: To provide orally acceptable compositions of flavonoid in a novel microparticulate and soluble form.SOLUTION: Provided is an orally acceptable composition comprising 0.5-8 wt% of particulate flavonoid hydrate with 50-1000 nm in average size, hyaluronic acid and a carrier containing nonionic surfactant suitable for oral administration, where the flavonoid is selected from flavone, flavonol, flavanone, flavanol, anthocyanidin and isoflavone. Provided is an orally acceptable composition in which the particulate flavonoid is 1 wt% or more of the composition, the composition can be a nutraceutical, dietary supplement, food additive or medical food, or as powder, pill or tablet. Also provided is a flavonoid enriched foodstuff comprising a microparticulate flavonoid hydrate of average size of 50-1000 nm, hyaluronic acid and a carrier suitable for oral administration comprising a nonionic surfactant, in the form of beverages, cereals or soups.SELECTED DRAWING: Figure 1【課題】微粒子、かつ、可溶性の新規形態のフラボノイドの経口的に許容可能な組成物の提供。【解決手段】５０～１０００ｎｍの平均サイズを有する、０．５～８重量％の微粒子フラボノイド水和物、ヒアルロン酸、及び非イオン性界面活性剤を含有する経口投与に適した担体、を含んでなる、経口的に許容可能な組成物で、フラボノイドが、フラボン、フラボノール、フラバノン、フラバノール、アントシアニジン、及びイソフラボンから選択される、経口的に許容可能な組成物微粒子フラボノイドが組成物の１重量％以上で、栄養補助食品、保健食品、食品添加剤、又は医療食品の形態、或いは、粉末、丸薬、又は錠剤、経口的に許容可能な組成物。５０～１０００ｎｍの平均サイズを有する微粒子フラボノイド水和物、ヒアルロン酸、及び非イオン性界面活性剤を含有する経口投与に適した担体、を含んでなる飲料、シリアル、又はスープの形態の、フラボノイド強化食品。【選択図】図１
