針對表皮生長因子受體的缺失突變體的抗體及其使用

• 收藏
• 分享

专利权人:

AMGEN FREMONT INC.

发明人:

WEBER, RICHARD,FENG, XIAO,FOORD, ORIT,GREEN, LARRY,GUDAS, JEAN,KEYT, BRUCE,LIU, YING,RATHANASWAMI, PALANI,RAYA, ROBERT,YANG, XIAO, DONG,CORVALAN, JOSE,FOLTZ, IAN,JIA, XIAO-CHI,KANG, JASPAL,KING, CHADW,理查德‧韋伯,馮曉,奧里特‧福德,拉里‧格林,琼‧古達斯,布魯斯‧基特,劉穎,帕拉尼‧拉塔納斯瓦米,羅伯特‧拉亞,楊曉東,COR

申请号：

HK15102456.6

公开号：

HK1201861A

申请日:

2015.03.10

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/