Richard F. Weber,Xiao Feng,Orit Foord,Larry L. Green,Jean M. Gudas,Bruce A. Keyt,Ying Liu,Palaniswami Rathanaswami,Robert Raya,Xiao Dong Yang,Jose R.F. Corvalan,Ian Foltz,Xiao-Chi Jia,Jaspal Singh Kan
申请号:
US16673234
公开号:
US20200062860A1
申请日:
2019.11.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.