The invention relates to compounds of the formula I:whereinA is a saturated or unsaturated hydrocarbon chain having a chain length of 4 to 6 carbon atoms, the hydrocarbon chain being unsubstituted or substituted by 1, 2 or 3 methyl groups；R1is selected from the group consisting of hydrogen, C1-C3alkyl and fluorinated C1-C3alkyl；R2is hydrogen, halogen, cyano, C1-C3alkyl, C1-C3alkoxy, fluorinated C1-C3alkyl or fluorinated C1-C3alkoxy；R3is selected from the group consisting of branched C4-C6alkyl and C3-C6cycloalkyl, andR4is C1-C6alkyl, C3-C6cycloalkyl, fluorinated C1-C3-alkyl and fluorinated C3-C6cycloalkyl.and the physiologically tolerated salts of these compounds and the N-oxides thereof.The invention also relates to a pharmaceutical composition that comprises at least one compound of the formula I and/or at least one physiologically tolerated acid addition salt thereof, and further to a method for treating disorders that respond beneficially to dopamine D3receptor antagonists or dopamine D3agonists, said method comprising administering an effective amount of at least one compound or physiologically tolerated acid addition salt of the formula I to a subject in need thereof.本發明係關於式I化合物：其中A 係具有4個至6個碳原子鏈長度的飽和或不飽和烴鏈，該烴鏈未經取代或經1個、2個或3個甲基基團取代；R1 係選自由氫、C1-C3烷基及氟化C1-C3烷基組成之群；R2 係氫、鹵素、氰基、C1-C3烷基、C1-C3烷氧基、氟化C1-C3烷基或氟化C1-C3烷氧基；R3 係選自由分支之C4-C6烷基及C3-C6環烷基組成之群，及R4 係C1-C6烷基、C3-C6環烷基、氟化C1-C3-烷基及氟化C3-C6環烷基。及此等化合物之生理學上可耐受之鹽及其N-氧化物。本發明亦關於一種醫藥組合物，其包含至少一種式I化合物及/或至少一種其生理學上可耐受之酸加成鹽，進一步關於一種用於治療對多巴胺D3受體拮抗劑或多巴腇D3激動劑有利反應之疾病的方法，該方法包括對有需要之個體投與有效量之至少一種式I之化合物或生理學上可耐受之酸加成鹽。
