CELL-PENETRATING BACTERIAL E3-UBIQITIN-LIGASES FOR USE IN IMMUNOTHERAPY

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专利权人:

WESTFÃLISCHE WILHELMS-UNIVERSITÃT MÜNSTER

发明人:

Marie-Luise Lubos,Alexander Schmidt,Christian Rueter

申请号：

US16537022

公开号：

US20200038493A1

申请日:

2019.08.09

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for use in immunotherapy. The present invention further relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for delivering cargo molecules into eukaryotic cells.

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