RODGERS, James D.,J.D.罗杰斯,J.D.羅傑斯,SHEPARD, Stacey,S.谢泼德,S.謝潑德,MADUSKUIE, Thomas P.,T.P.马杜斯亏,T.P.馬杜斯虧,WANG, Haisheng,H.王,FALAHATPISHEH, Nikoo,N.法拉哈特皮谢,N.法拉哈特皮謝,RAFALSKI, Maria,M.拉法尔斯基,M.拉法爾斯基,ARVAN,J.D.罗杰斯,J.D.羅傑斯,S.谢泼德,S.謝潑德,T.P.马杜斯亏,T.P.馬杜斯虧,H.王,N.法拉哈特皮谢,N.法拉哈特皮謝,M.拉法尔斯基,M.拉法爾斯基
申请号:
MOJ002521
公开号:
MOJ002521B
申请日:
2017.03.01
申请国别(地区):
MO
年份:
2017
代理人:
摘要:
Pyrrolo- that the bright Ti Gong Miscellaneous aryl of this Hair replaces [2,3-b] pyridine He Miscellaneous aryl replace pyrrolo- [2,3-b] pyrimidine, the work And of the face Tone Festival Two mind kinases controls the disease of the work phase Off of the face Treatment With Two mind kinases with what, including, such as disease, skin Skin disease, myeloproliferative disorder, cancer and the Other diseases of immune-phase Off.本發明提供雜芳基取代的吡咯并[2,3-b]吡啶和雜芳基取代的吡咯并[2,3-b]嘧啶,其調節兩面神激酶的活性並用於治療與兩面神激酶的活性相關的疾病,包括,例如免疫-相關的疾病、皮膚病、脊髓增生性疾病、癌及其它疾病。