CO CRYSTALS OF (S) -N-METHYL-8- (1 - ((2'-METHYL- [4,5'-BIPYRIMIDIN] -6-YL) AMINO) PROPAN-2-YL) QUINOLIN-4-CARBOXAMIDE AND DEUTERATED DERIVATIVES THEREOF AS DNA-PK INHIBITORS
NTI-ADDAE, Kwame, Wiredu,O'NEIL, Simon Adam,ZHANG, Yuegang,MUDUNURI, Praveen,VAN ALSTEN, John Gregg,SONG, Bin,STAVROPOULOS, Kathy,STROHMEIER, Mark,WALDO, Michael,NAVAMAL, Mettachit,KADIYALA, Irina Nik
申请号：
DK18188034
公开号：
DK3424920T3
申请日:
2014.10.17
申请国别(地区):
DK
年份:
2020
代理人:
摘要：
The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: wherein each of R 1 and R 2 is H or 2 H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.
