CO CRYSTALS OF (S) -N-METHYL-8- (1 - ((2'-METHYL- [4,5'-BIPYRIMIDIN] -6-YL) AMINO) PROPAN-2-YL) QUINOLIN-4-CARBOXAMIDE AND DEUTERATED DERIVATIVES THEREOF AS DNA-PK INHIBITORS
NTI-ADDAE, Kwame, Wiredu,O'NEIL, Simon, Adam,ZHANG, Yuegang,VAN ALSTEN, John Gregg,SONG, Bin,STAVROPOULOS, Kathy,STROHMEIER, Mark,WALDO, Michael,NAVAMAL, Mettachit,KADIYALA, Irina Nikolaevna,MUDUNURI,,ONEIL, Simon, Adam
申请号：
DK14799578
公开号：
DK3057953T3
申请日:
2014.10.17
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: wherein each of R 1 and R 2 is H or 2 H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.
