David Edward Allison;Lee R. Brettman;Judith A. Fox
发明人:
Lee R. Brettman,Judith A. Fox,David Edward Allison
申请号：
US13204139
公开号：
US20120034243A1
申请日:
2011.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed is a method for treating a human having a disease associated with leukocyte infiltration of mucosal tissues, comprising administering to said human an effective amount of a human or humanized immunoglobulin or antigen-binding fragment thereof having binding specificity for α4β7 integrin. Preferably, no more than 8 mg immunoglobulin or fragment per kg body weight are administered during a period of about one month.
