Lee R. Brettman,Judith A. Fox,David Edward Allison
申请号：
US16179157
公开号：
US20200002423A1
申请日:
2018.11.02
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed is a method for treating a human having a disease associated with leukocyte infiltration of mucosal tissues, comprising administering to said human an effective amount of a human or humanized immunoglobulin or antigen-binding fragment thereof having binding specificity for α4β7 integrin. Preferably, no more than about 8 mg immunoglobulin or fragment per kg body weight are administered during a period of about one month.
