The subject invention provides a pharmaceutical composition containing laquinimod or a pharmaceutically acceptable salt thereof, and a compound of N-ethyl-N-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinolinecarboxamide or a salt thereof.本發明提供一種醫藥組合物,其含有拉喹莫德(laquinimod)或其醫藥學上可接受之鹽及化合物N-乙基-N-苯基-1,2-二氫-4,5-二-羥基-1-甲基-2-酮基-3-喹啉羥醯胺或其鹽。