PROBLEM TO BE SOLVED: To provide a respiration region volume inhibitor which forms a coating film in a respiration region, the inhibitor having coating film formation as the main component thereof.SOLUTION: Film forming components of 0.004-200 g/application, preferably 0.07-20 g/application, and even more preferably coating film forming components of 0.5-5g/application are used by being applied to emphysema-suffering pulmonary alveolar parenchyma in a human respiratory region the medicine reduces the volume of emphysema-suffering alveolar sacs or pulmonary alveoli by means of the respiration region volume inhibitor which forms the coating film in the respiration region, the inhibitor having coating film formation as the main component thereof.COPYRIGHT: (C)2012,JPO&INPIT【課題】被膜形成を主成分とした呼吸域内に被膜を形成する呼吸域体積抑制剤の提供。【解決手段】1回あたり0.004~200g/手技の被膜形成成分が、好ましくは0.07~20g/手技、さらに好ましくは0.5~5g/手技の被膜形成成分が、ヒトの呼吸域内の気腫化した肺胞実質に投与されるように用いられ、被膜形成を主成分とした呼吸域内に被膜を形成する呼吸域体積抑制剤により気腫化した肺胞または肺胞嚢の容量を低減する薬剤。【選択図】なし