Ralph Casale;Alexander B. Baguisi;Alan S. Lader;Steven A. Kates;Reinier Beeuwkes
发明人:
Alexander B. Baguisi,Reinier Beeuwkes,Ralph Casale,Steven A. Kates,Alan S. Lader
申请号:
US13319839
公开号:
US20120135932A1
申请日:
2010.05.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates, in some embodiments, to compositions comprising a substantially pure compound represented by Structural Formula (I) and methods of using such compounds to activate cytoprotective kinases. In additional embodiments, the invention relates to methods for treating an ischemia or an ischemia-reperfusion injury in a subject, comprising administering to the subject an effective amount of a compound of the invention (e.g., in multiple doses). The values and preferred values of the variables in Structural Formula (I) are defined herein.