CHAPLEO, CHRISTOPHER BOURNE,克利斯朵夫柏尼恰普罗,克利斯朵夫柏尼恰普羅,LEWIS, JOHN WILLIAM,约翰威廉路易士,約翰威廉路易士
申请号：
TW096110534
公开号：
TWI501969B
申请日:
2007.03.27
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
Ester derivatives of the phenolic hydroxyl group of buprenorphine are described that can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential.本發明說明丁基原啡因(buprenorphine)之酚性羥基之酯衍生物其可用於治療鴉片成癮性及/或減輕嚴重疼痛。該酯類具有增強之生物利用率、增強之持續作用時間、及減低之濫用可能性。
