E. CONNOLLY, JOHN EDWARD,寇那里 约翰,寇那里 約翰,VU, DANG L.,武 丹L,武 丹L
申请号：
TW106124862
公开号：
TW201806969A
申请日:
2017.07.25
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
Chimeric Antigen Receptors (CARs) comprising a costimulatory sequence which is, or which is derived from, the intracellular domain of CD226, or a fragment thereof, are disclosed. Also disclosed are compositions comprising such CARs, and uses and methods using the same.揭露包含一種共刺激序列之嵌合抗原受體(CAR),該共刺激序列係身為或衍生自CD226的細胞內域或其片段。亦揭露包含該等嵌合抗原受體的組成物,及其用途與使用方法。
