PREPARATION CONTAINING TETRACYCLIC COMPOUND AT HIGH DOSE

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专利权人:

Chugai Seiyaku Kabushiki Kaisha

发明人:

Takashi TOMIMATSU,Kensuke OKAZAKI,Yumi OGAWA,Takahiro YAMAMURA

申请号：

US16508760

公开号：

US20200038407A1

申请日:

2019.07.11

申请国别(地区):

US

年份:

2020

代理人:

摘要：

An improved solubility of a pharmaceutical composition or formulation containing a large amount of 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile or a salt thereof can be achieved by forming granules of the compound or salt thereof and allowing the granules to be present together with a disintegrating agent.

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