#$%^&*AU2020230293A120201001.pdf#####Abstract An improved solubility of a pharmaceutical composition or formulation containing a large amount of 9-ethyl-6,6dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11dihydro-5H-benzo[bicarbazole-3-carbonitrile or a salt thereof can be achieved by forming granules of the compound or salt thereof and allowing the granules to be present together with a disintegrating agent.