Gilnam Lee,Chul Soo Lim,Han Won Cho,Jeongbeob Seo,Albert C. Gyorkos,Suk Young Cho,Eun Kyung Choi,Choung Soo Kim,Jung Jin Hwang,Jin Sung Kim,Hee Jung An,Yong Wha Moon
申请号:
US14622447
公开号:
US09422298B2
申请日:
2015.02.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.