Albert Charles Gyorkos;Choung Soo Kim;Eun Kyung Choi;Gilnam Lee;Chul Soo Lim;Jung Jin Hwang;Han Won Cho;Suk Young Cho;Jeongbeob Seo
发明人:
Gilnam Lee,Chul Soo Lim,Han Won Cho,Jeongbeob Seo,Albert Charles Gyorkos,Suk Young Cho,Eun Kyung Choi,Choung Soo Kim,Jung Jin Hwang
申请号:
US13423950
公开号:
US20120238587A1
申请日:
2012.03.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.