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Apparatus and methods for high throughput sperm sorting
专利权人:
INGURAN LLC
发明人:
Sedoglavich Nemanya,Morad Blair,Perrault Jr. Donald Francis,Koksal Erin,Sharpe Johnathan Charles,Buchanan Kris
申请号:
NZ63055914
公开号:
NZ630559A
申请日:
2014.03.14
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
A sperm sorting system includes at least one flow channel formed in a substrate, the flow channel having an sample inlet that receives sample, an inspection region, a first outlet, a second outlet, and a core stream forming geometry. The core streaming forming geometry includes a lateral fluid focusing region 520 on the same plane as the sample inlet, a first vertical fluid focusing channel 524 and a second vertical fluid focusing channel 526. The first vertical fluid focusing channel contacts the flow channel at a first location and the second vertical fluid focusing channel contacts the flow channel from a second location so that the first and second vertical fluid focusing channels have opposite vertical positions and so that the flow channel is only contacted on one side at the first and second locations respectively. At least one diverting mechanism is in communication with each of the at least one flow channels to selectively divert sperm in the at least one flow channel away from the first outlet, and an electromagnetic radiation source is provided for illuminating sperm at the inspection region. The system includes a detector aligned to measure sperm characteristics in the inspection region of the at least one flow channel an analyzer in communication with the detector to determine sperm characteristics a controller in communication with the analyzer for selectively activating the diverting mechanism based on measured sperm characteristics and a collection vessel in communication with the second outlet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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