Peptide derivatives for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation
Anders Grubb,Franciszek Kasprzykowski,Ulf Lerner,Beata Zolnowska,Regina Kasprzykowska
申请号:
US14257255
公开号:
US09169289B2
申请日:
2014.04.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compounds of formula R1-A-NH—CH(R2)—CO—R3 are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.