Thaxton, Shad C.,Mirkin, Chad A.,McMahon, Kaylin,Tripathy, Sushant,Mutharasan, Raja Kannan,Leander, David M.,Luthi, Andrea
申请号：
AU2011207563
公开号：
AU2011207563B2
申请日:
2011.01.19
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement； for instance, a nanostructure core may be surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent.
