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Synthetic nanostructures including nucleic acids and/or other entities
专利权人:
Northwestern University
发明人:
C. Shad Thaxton,Chad A. Mirkin,Kaylin M. McMahon,Sushant Tripathy,Raja Kannan Mutharasan,David M. Leander,Andrea Luthi
申请号:
US14215569
公开号:
US09216155B2
申请日:
2014.03.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanostructure core may be surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent.
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中国工程科技知识中心
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