C. Shad Thaxton,Chad A. Mirkin,Kaylin M. McMahon,Sushant Tripathy,Raja Kannan Mutharasan,David M. Leander,Andrea Luthi
申请号：
US14215569
公开号：
US09216155B2
申请日:
2014.03.17
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement； for instance, a nanostructure core may be surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent.
