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超高速崩解錠劑及其製造方法
专利权人:
DAICEL CORPORATION
发明人:
HASHIKAWA, NAOHIRO,桥川尙弘,橋川尙弘,OKABAYASHI, TOMOHITO,冈林智仁,岡林智仁,TAKIGAWA, YOSHIHISA,泷川嘉久,瀧川嘉久,UETOMO, ATSUHIRO,上友淳弘
申请号:
TW104141084
公开号:
TW201636008A
申请日:
2015.12.08
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
The purpose of the present invention is to provide: an oral disintegrating tablet (a very rapidly disintegrating tablet) having extremely high disintegrating properties (a short disintegrating time); and a simple method whereby it becomes possible to produce the very rapidly disintegrating tablet without carrying out lyophilization that is a complicated procedure. The present invention relates to: an oral disintegrating tablet having a specific surface area of 1.50 to 2.50 mm2/mg and a weight of 10 to 50 mg, and particularly having a disintegrating time of 7 seconds or shorter in water and a disintegrating time of 5 seconds or shorter in the oral cavity; a method for producing the oral disintegrating tablet; a disintegrating particle composition which is used in the production method; and others.本發明之目的在於提供一種具備極高之崩解性(較短之崩解時間)之口腔內崩解錠劑(超高速崩解錠劑)、及可不經由冷凍乾燥等繁雜之操作而製造此種超高速崩解錠劑之簡便之方法。本發明係關於一種比表面積為1.50~2.50mm2/mg且重量為10~50mg,尤其是水中崩解時間為7秒以下、口腔內崩解時間為5秒以下之口腔內崩解錠劑、該口腔內崩解錠劑之製造方法、及該製造方法中使用之崩解性粒子組成物等。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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