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超高速崩解錠劑及其製造方法
专利权人:
DAICEL CORPORATION
发明人:
OKABAYASHI, TOMOHITO,冈林智仁,岡林智仁,UETOMO, ATSUHIRO,上友淳弘,HASHIKAWA, NAOHIRO,桥川尙弘,橋川尙弘,HIRAMURA, TAKAHIRO,平邑隆弘,MORITA, TETSURO,森田哲郎,IKEDA, KIMIKO,池田君子
申请号:
TW105126755
公开号:
TW201717916A
申请日:
2016.08.22
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
The purpose of the present invention is to provide: an oral disintegrating tablet (a super-rapid disintegrating tablet), which has a large weight and a relatively small thickness and has an extremely high disintegrating property (a short disintegration time); and a simple method for producing the super-rapid disintegrating tablet without the need of carrying out lyophilization which is a complicated operation. The present invention relates to: an oral disintegrating tablet which has a specific surface area of 1.50 to 4.00 mm2/mg and a weight of 100 to 300 mg, and particularly has a disintegration time in water of 7 seconds or shorter and a disintegrating time in oral cavity of 6 seconds or shorter; a method for producing the oral disintegrating tablet; and a disintegrating particle composition which can be used for the production method.本發明之目的在於提供口腔內崩解錠劑(超高速崩解錠劑)、及可不經過冷凍乾燥等繁雜操作而製造此種超高速崩解錠劑之簡便之方法,該口腔內崩解錠劑為重量較大且相對較薄之錠劑並且具有極高之崩解性(較短之崩解時間)者。本發明係關於一種口腔內崩解錠劑、該口腔內崩解錠劑之製造方法、及用於該製造方法中之崩解性粒子組合物,上述口腔內崩解錠劑之比表面積為1.50~4.00mm2/mg,及重量為100~300mg,尤其水中崩解時間為7秒以下,且口腔內崩解時間為6秒以下。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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