An assembly of throat lozenge and applicator has improved therapeutic properties, further augmented by following a method consisting of a heating procedure using a flavor or efficacy-enhancing liquid. The throat lozenge is molded onto a distal end of an applicator adapted for holding the throat lozenge at a desired location within the mouth. The lozenge containing a plurality of cavities of specific depth and placement on the upper surface or shell of the lozenge, that following a proscribed method are filled with a therapeutic liquid. The combination of all elements of the invention and following the method results in improved perceived efficacy.