The invention concerns an ocular iontophoresis device (10) for delivering at least one active substance to an eyeball (100), comprising: - a reservoir (13) configured for receiving at least one active substance, - a wall (11) comprising a circular distal end (14) configured for being positioned on an ocular surface (101) of the eyeball and surrounding the cornea (102) and a part of the sclera (103) of the eyeball (100), - a first electrode (15) configured to be positioned in front of the part of the sclera (103) which is surrounded by the wall when the wall is in place on said ocular surface, said first electrode being configured for delivering a first current density to at least one active substance of the reservoir, - a second electrode (16) configured to be positioned in front of the cornea when the wall is in place on said ocular surface, said second electrode being configured for delivering a second current density to at least one active substance of the reservoir, and - at least one controller (17, 18) for independently controlling said first and second electrodes.