Inhibit the pyrimidine derivatives of HIV农业专利-农业学术服务平台

发明人:: J．E．G．古勒蒙特,P．帕兰德吉安,P．帕蘭德吉安,M．R．德乔格,M．R．德喬格,L．M．H．科伊曼斯,H．M．温克斯,H．M．溫克斯,F．F．D．达雅尔特,F．F．D．達雅爾特,J．赫勒斯,K．J．A．范亚肯,K．J．A．范亞肯,P．J．勒维,P．J．勒維,P．A．J．詹森,J.E.G.古勒蒙特,P.帕兰德吉安,P.帕蘭德吉安,M.R.德乔格,M.R.德喬格,L.M.H.科伊曼斯,H.M.温克斯,H.M.溫克斯,F.F.D.达雅尔特,F.F.D.達雅爾特,J.赫勒斯,K.J.A.范亚肯,K.J.A.范亞肯,P.J.勒维,P.J.勒維,P.A.J.詹森

摘要：: The bright pyrimidine derivatives for being related to inhibiting HIV of this Hair. Ju Body is related to that formula below (I), the HIV Complex System of acceptable Jia Cheng Which, quaternary ammonium and Li Bodyization Learn Iso Agencies Body inhibit Elixirs on its N- oxide, Drug Learn, wherein respectively symbol No. has and illustrates to Ding described in Books Righteousness； The bright It of this Hair is related to as Qi System Prepare method of the purposes , of Drug object and the Drug Wu Group containing its Men closes object.本發明涉及抑制HIV的嘧啶衍生物。具體涉及以下的式(I)、其N-氧化物、藥學上可接受的加成鹽、季銨以及立體化學異構體的HIV複製抑制劑，其中各符號具有說明書所述的定義；本發明還涉及作爲藥物的用途，其製備方法以及含它們的藥物組合物。