Disclosed is a Helicobacter pylori eradicating agent comprising a metal ion having an antibacterial activity, L-cysteine and L-ascorbic acid as the main ingredients and further comprising a surfactant excluding a nonionic surfactant. The Helicobacter pylori eradicating agent is highly safe, and can be used in combination with at least one antibiotic selected from the group consisting of amoxicillin, clarithromycin and a proton pump inhibitor to substantially kill a Helicobacter pylori cell that has been difficult to eradicate heretofore in a carrier of the Helicobacter pylori cell within a short period. Also disclosed is a Helicobacter pylori eradication method.