The present invention relates to a biocompatible oxidizing polysaccharide, a natural protein polymer, and a double crosslinked-structured hemostatic agent comprising a natural enzyme crosslinking agent, and a method for producing the same. The biocompatible hemostatic agent having a double crosslinked structure, produced according to the present invention, is capable of decomposing in vivo, so that the agent has excellent biocompatibility, is non-toxic to cells or tissues, has a high water absorption capacity and an excellent hemostatic function, thereby quickly stopping bleeding. Therefore, the agent is expected to be applied as a medical hemostatic agent.La présente invention concerne un polysaccharide oxydant biocompatible, un polymère protéique naturel, et un agent hémostatique à double structure réticulée comprenant un agent de réticulation de type enzyme naturelle, et son procédé de production. Lagent hémostatique biocompatible à double structure réticulée, produit selon la présente invention, est capable de se décomposer in vivo, de sorte que lagent possède une excellente biocompatibilité, est non toxique vis-à-vis des cellules ou des tissus, a une capacité dabsorption deau élevée et une excellente fonction hémostatique, arrêtant ainsi rapidement le saignement. Par conséquent, lagent devrait être appliqué à titre dagent hémostatique à visée médicale.본 발명은 생체친화성을 갖는 산화 다당류, 천연 단백질 고분자 및 천연 효소 가교제를 포함하는 이중 가교구조의 지혈제 및 그 제조방법에 관한 것이다. 본 발명에 따라 제조된 이중 가교구조의 생체친화성 지혈제는 생체 내 분해가 가능하여 생체친화성이 우수할 뿐만 아니라, 세포 혹은 조직에 독성이 없고 높은 체수분 흡수력과 뛰어난 지혈 작용으로 빠르게 출혈을 막을 수 있어, 의료용 지혈제로서 응용이 기대된다.
