The present invention relates to compositions comprising a recombinant attenuated Listeria strain expressing a truncated ActA and fusion proteins thereof and methods of using the same for inducing anti-disease immune responses, and treatment of the same, including a tumor growth or cancer. In particular, the invention relates to the treatment of a tumor growth or cancer using a live attenuated recombinant Listeria strain that expresses a fusion protein of a truncated ActA fused to an antigen.本發明係有關於包含表現經截斷的ActA及其融合蛋白的重組體減毒李斯特氏菌株之組成物及其使用於誘生抗病免疫反應之方法,及其治療,包括腫瘤生長或癌症的治療。特別,本發明係有關於使用表現經截斷的ActA融合至抗原的融合蛋白之活減毒重組體李斯特氏菌株用於腫瘤生長或癌症的治療。
