ГУДНАУ Дж. Роберт Алан (US),ГАМИЛЬТОН Мэтью Майкл (US),СИДДУРИ Ачютарао (US)
申请号:
RU2014132830
公开号:
RU2014132830A
申请日:
2013.01.24
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A compound of formula I: or a pharmaceutically acceptable salt or ester thereof in which n is from 1 to 24 and in which: R1 is selected from the group consisting of: (1) a compound of the formula: in which m is from 0 to 3 and G is selected from the group consisting of: (2) a compound of the formula: in which m is from 0 to 3, R4 and R5 are independently hydrogen or halogen, W is O or CH, and G is selected from the group consisting of: and (3) a compound of the formula: R2 is selected from the group consisting of: (1) compounds of the formula: (2) compounds of the formula: (3) compounds of the formula: and (4) compounds of the formula: in which R3 is a conjugated moiety and X is either ce y, either a compound of formula: 2. A compound according to claim 1, wherein R1 is a compound of the formula: wherein m is from 0 to 3.3. A compound according to claim 1, wherein R1 is a compound of the formula: where m is from 0 to 3.4. The compound of claim 1, wherein R1 is a compound of the formula: wherein m is from 0 to 3.5. The compound of claim 1, wherein R1 is a compound of the formula: wherein m is from 0 to 3.6. A compound according to claim 1, wherein R1 is a compound of the formula: wherein m is 0 to 3, R4 and R5 are hydrogen or halogen and W is O or CH.7. A compound according to claim 1, wherein R1 is a compound of the formula: wherein m is 0 to 3, R4 and R5 are hydrogen or halogen and W is O or CH. A compound according to claim 1, wherein R1 is a compound of the formula: wherein m is 0 to 3, R4 and R5 are hydrogen or halogen and W is O or CH. A compound according to claim 1, wherein R1 is a compound of the formula: wherein m is from 0 to 3, R4 and R5 are hydrogen or halogen, and W is O or CH. A compound according to claim 1, wherein R1 is a compound of the formula: 11. A compound according to any of the preceding claims. 1-10,1. Соединение формулы I:или его фармацевтически приемлемая соль или эфир в котором n равно от 1 до 24 и в котором:R1 выбран из группы, состоя