DI-HIDROPIRIMIDINONAS BICÍCLICAS SUBSTITUÍDAS E SUA UTILIZAÇÃO COMO INIBIDORES DE ATIVIDADE DE ELASTASE DE NEUTRÓFILOS

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

RALF ANDERSKEWITZ,THORSTEN OOST,CHRISTIAN GNAMM,HOLGER HOESCH,UWE JÖRG RIES,GERD MORSCHHAEUSER,STEFAN PETERS

申请号：

PT15744229

公开号：

PT3174861T

申请日:

2015.07.30

申请国别(地区):

PT

年份:

2019

代理人:

摘要：

This invention relates to substituted bicyclic dihydropyrimidinones of formula 1and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/