DIHYDROPYRIMIDINONES BICYCLIQUES SUBSTITUEES ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE L'ACTIVITE DE L'ELASTASE NEUTROPHILE

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

OOST, THORSTEN,ANDERSKEWITZ, RALF,GNAMM, CHRISTIAN,HOESCH, HOLGER,MORSCHHAEUSER, GERD,PETERS, STEFAN,RIES, UWE JOERG

申请号：

CA2956745

公开号：

CA2956745A1

申请日:

2015.07.30

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/