ARNE SKERRA,Gerald Beste,Frank Schmidt,Thomas Stibora
申请号：
US15092566
公开号：
US20160280747A1
申请日:
2016.04.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. A like immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.
