Arne Skerra,Gerald Beste,Frank Schmidt,Thomas Stibora
申请号：
US13423666
公开号：
US08536307B2
申请日:
2012.03.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to the production of novel proteins exhibiting binding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. Like immunoglobulin, the anticalin thus obtained can be used to identify or bind molecular structures.
