BRANDENBURG BOERRIES,VOGELS RONALD,KOLKMAN JOOST A,FRIESEN ROBERT HEINZ EDWARD
申请号:
IN201717030913
公开号:
IN201717030913A
申请日:
2017.08.31
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention relates to monomeric and multimeric binding molecules that are capable of specifically binding to hemagglutinin (HA) of at least two influenza A virus strains said strains comprising HA of two different HA subtypes from phylogenetic group 2 or capable of specifically binding to hemagglutinin (HA) of at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2 or capable of specifically binding to hemagglutinin (HA) of at least one influenza B virus strain. The binding molecules preferably are also capable of neutralizing at least two influenza A virus strains from phylogenetic group 2 or capable of neutralizing at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2 or capable of specifically neutralizing at least one influenza B virus strain.