KAUL, RAMESH,MCEACHERN, ERNEST J.,VOCADLO, DAVID J.,ZHOU, YUANXI,LIU, KUN,SELNICK, HAROLD G.,WEI, ZHONGYONG,MU, CHANGWEI,WANG, YAODE,WANG, XIAONA
申请号：
EP12765063
公开号：
EP2691407A4
申请日:
2012.03.20
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention provides compounds of formula (I) with substituents as specified in Claim 1 for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceuticals compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to over-expression of O-GlcNAcase or accumulation of O-GlcNac.
