Ramesh Kaul,Ernest J. McEachern,David J. Vocadlo,Yuanxi Zhou,Kun Liu,Harold G. Selnick,Zhongyong Wei,Changwei Mu,Yaode Wang,Xiaona Wang
申请号:
US14008388
公开号:
US09718854B2
申请日:
2012.03.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides compounds of formula (I) with substituents as specified in claim 1 for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceuticals compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to over-expression of O-GlcNAcase or accumulation of O-GlcNac.