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HCV NS3-NS4A Protease Inhibition
专利权人:
Vertex Pharmaceuticals Incorporated
发明人:
Lin, Chao,Taylor, William P.
申请号:
AU2012200209
公开号:
AU2012200209A1
申请日:
2012.01.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012200209A120120202.pdf#####ABSTRACT The present invention relates to inhibiting the activity of non-genotype 1 hepatitis C virus (HCV) NS3-NS4A protease activity. More particularly, the invention relates to inhibiting the activity of the protease from HCV genotype-2 or HCV 5 genotype-3. The methods of the invention emply inhibitors that act by interfering with the life cycle of the HCV and are also useful as antiviral agents. The invention further relates to compositions comprising such compounds either for ex vivo use or for administration to a patient suffering from genotype-2 or genotype-3 HCV infection. The invention also relates to methods of treating an HCV infection 10 in a patient by administering a composition comprising a compound of this invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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