COMPOSITION FOR PREVENTING, IMPROVING OR TREATING OF T H2-MEDIATED IMMUNE DISEASE COMPRISING EXTRACTS FROM RANUNCULUS JAPONICUS, EXTRACTS FROM ILLICIUM RELIGIOSUM, EXTRACTS FROM CHLORANTHUS JAPONICUS OR EXTRACTS FROM EUCOMMIA ULMOIDES
SHON, DONG HWA,손동화,SHIN, HEE SOON,신희순,CHAI, OK HEE,채옥희,BAE, MIN JUNG,배민정,CHOI, DAE WOON,최대운,JUNG, SUN YOUNG,정선영,SEE, HYE JEONG,시혜정,LEE, SO YOUNG,이소영,DO, JEONG RYONG,도정룡,JUNG, SUNG KEUN,정성근,CHUNG, MIN,SHON, DONG HWAKR,SHIN, HEE SOONKR,CHAI, OK HEEKR,BAE, MIN JUNGKR,CHOI, DAE WOONKR,JUNG, SUN YOUNGKR,SEE, HYE JEONGKR,LEE, SO YOUNGKR,DO, JEONG RYONGKR,JUNG, SUNG KE
申请号：
KR1020140079150
公开号：
KR1020160001806A
申请日:
2014.06.26
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a composition for preventing, mitigating, or treating Th2-mediated immune diseases, comprising one or more extracts selected from the group consisting of a Ranunculus japonicus Thunb. extract, an Illicium religiosum Siebold & Zucc. extract, a Chloranthus japonicus Sieb. extract, and an Eucommia ulmoides OLIV. extract. According to the present invention, the extracts have activities of inhibiting IL-4 generation and inhibiting mast cell degranulation, thereby preventing, mitigating, or treating Th2-mediated immune diseases.본 발명은 미나리아재비(Ranunculus japonicus) 추출물, 붓순나무(Illicium religiosum) 추출물, 홀아비꽃대(Chloranthus japonicus) 추출물 및 두충(Eucommia ulmoides) 추출물로 구성된 군으로부터 선택되는 하나 이상의 추출물을 유효성분으로 포함하는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따르면, 상기 추출물은 IL-4 생성 억제 및 비만세포의 탈과립 억제 활성을 가짐으로 Th2-매개 면역 질환을 예방, 개선 또는 치료할 수 있다.
